Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520950 | 0.73 | — | — | |
| SCHEMBL4899542 | 0.67 | HRH1 (0.39) | HRH1HRH4FDPSBAZ2BCYP2A6 | |
| SCHEMBL12778269 | 0.67 | SCN10A (0.35) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL11339878 | 0.65 | HRH4 (0.38) | HRH1HRH4FDPSBAZ2BCYP2A6 | |
| Ammonia Solution, Strong SCHEMBL29243752 | 0.65 | HRH1 (0.38) | HRH1HRH4FDPSBAZ2BCYP2A6 | |
| SCHEMBL12778728 | 0.65 | HMBS (0.43) | SCN10A | |
| SCHEMBL5665905 | 0.64 | FDPS (0.47) | HRH1HRH4FDPSBAZ2B | |
| SCHEMBL25808354 | 0.64 | HRH1 (0.36) | HRH1HRH4FDPSBAZ2BCYP2A6 | |
| SCHEMBL24427240 | 0.64 | SCN10A (0.44) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL12777890 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050160-A1 | PHARMACEUTICALS, COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2011-04-28 | — | — | WO | disclosed |