Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282245 | 0.65 | COMT (0.31) | — | |
| SCHEMBL12778268 | 0.65 | HRH2 (0.35) | POLBL3MBTL1 | |
| SCHEMBL12778250 | 0.60 | TRPA1 (0.39) | POLBL3MBTL1 | |
| SCHEMBL22199006 | 0.58 | ALDH1A1 (0.32) | — | |
| SCHEMBL17655239 | 0.58 | — | — | |
| SCHEMBL12777847 | 0.58 | CLK2 (0.33) | — | |
| SCHEMBL17198677 | 0.56 | NOTUM (0.33) | — | |
| SCHEMBL5278166 | 0.56 | — | — | |
| SCHEMBL15858201 | 0.56 | — | — | |
| SCHEMBL18663271 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050160-A1 | PHARMACEUTICALS, COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2011-04-28 | — | — | WO | disclosed |