Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 4/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12779102 | 0.93 | MAPT (0.49) | L3MBTL1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL12779092 | 0.89 | MAPT (0.44) | L3MBTL1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL12779122 | 0.88 | NPC1 (0.46) | L3MBTL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL12779319 | 0.86 | CCR5 (0.42) | L3MBTL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL12779173 | 0.86 | MAPT (0.41) | L3MBTL1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL12779105 | 0.85 | NPC1 (0.49) | L3MBTL1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL12779312 | 0.85 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL12779177 | 0.84 | P2RX1 (0.41) | L3MBTL1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL12779494 | 0.84 | CCR5 (0.38) | L3MBTL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL12779062 | 0.83 | TRPA1 (0.48) | L3MBTL1NPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906538-B2 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |