Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12779257 | 0.93 | MRGPRX4 (0.41) | MRGPRX4SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL12779267 | 0.92 | MRGPRX4 (0.44) | MRGPRX4SMN1; SMN2NPC1RAB9APPARG | |
| SCHEMBL12779405 | 0.90 | S1PR1 (0.39) | MRGPRX4SMN1; SMN2NPC1RAB9APPARG | |
| SCHEMBL12779127 | 0.90 | PPARG (0.41) | MRGPRX4SMN1; SMN2NPC1RAB9APPARG | |
| SCHEMBL12779299 | 0.88 | MRGPRX4 (0.47) | MRGPRX4SMN1; SMN2NPC1RAB9APPARG | |
| SCHEMBL12779391 | 0.87 | ALDH1A1 (0.41) | MRGPRX4SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL12779393 | 0.87 | MRGPRX4 (0.40) | MRGPRX4SMN1; SMN2NPC1RAB9APPARG | |
| SCHEMBL12779351 | 0.86 | NPC1 (0.51) | MRGPRX4SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL12779356 | 0.85 | MRGPRX4 (0.48) | MRGPRX4SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL12779279 | 0.84 | MRGPRX4 (0.44) | MRGPRX4NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906538-B2 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |