Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 3/20 | 0.37 |
| ▸ | WDR48 | Q8TAF3 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12779257 | 0.94 | MRGPRX4 (0.41) | S1PR1MRGPRX4KMT2AMEN1MAPT | |
| SCHEMBL12779267 | 0.93 | MRGPRX4 (0.44) | S1PR1MRGPRX4KMT2AGFERSMN1; SMN2 | |
| SCHEMBL12779127 | 0.91 | PPARG (0.41) | S1PR1MRGPRX4KMT2AGFERSMN1; SMN2 | |
| SCHEMBL12779261 | 0.90 | MRGPRX4 (0.38) | S1PR1MRGPRX4KMT2AGFERSMN1; SMN2 | |
| SCHEMBL12779299 | 0.89 | MRGPRX4 (0.47) | MRGPRX4KMT2AGFERSMN1; SMN2NPC1 | |
| SCHEMBL12779391 | 0.88 | ALDH1A1 (0.41) | S1PR1MRGPRX4KMT2AMEN1MAPT | |
| SCHEMBL12779393 | 0.88 | MRGPRX4 (0.40) | S1PR1MRGPRX4KMT2AUSP1WDR48 | |
| SCHEMBL12779351 | 0.87 | NPC1 (0.51) | MRGPRX4KMT2AMEN1MAPTUSP1 | |
| SCHEMBL12779356 | 0.86 | MRGPRX4 (0.48) | S1PR1MRGPRX4MAPTSMN1; SMN2NPC1 | |
| SCHEMBL12779279 | 0.85 | MRGPRX4 (0.44) | MRGPRX4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906538-B2 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |