Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12779257 | 0.89 | MRGPRX4 (0.41) | MRGPRX4S1PR1RAB9ANPC1LMNA | |
| SCHEMBL12779267 | 0.88 | MRGPRX4 (0.44) | MRGPRX4S1PR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12779391 | 0.87 | ALDH1A1 (0.41) | MRGPRX4S1PR1RAB9ANPC1LMNA | |
| SCHEMBL12779405 | 0.86 | S1PR1 (0.39) | MRGPRX4S1PR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12779127 | 0.86 | PPARG (0.41) | MRGPRX4S1PR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12779261 | 0.85 | MRGPRX4 (0.38) | MRGPRX4S1PR1RAB9ANPC1LMNA | |
| SCHEMBL12779431 | 0.84 | MRGPRX4 (0.45) | MRGPRX4S1PR1RAB9ANPC1NOTUM | |
| SCHEMBL12778493 | 0.83 | ALDH1A1 (0.38) | MRGPRX4RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL12779299 | 0.83 | MRGPRX4 (0.47) | MRGPRX4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12779393 | 0.83 | MRGPRX4 (0.40) | MRGPRX4S1PR1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906538-B2 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |