Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48258 | 0.77 | ERAP1 (0.61) | GDAACHESLC6A5MAPTTYRO3 | |
| SCHEMBL29385750 | 0.77 | ERAP1 (0.61) | GDAACHESLC6A5MAPTTYRO3 | |
| SCHEMBL13354614 | 0.75 | GDA (0.47) | GDAACHESLC6A5MAPTTYRO3 | |
| SCHEMBL1002106 | 0.75 | ACHE (0.42) | GDAACHESLC6A5MAPTTYRO3 | |
| SCHEMBL38855 | 0.72 | PDPK1 (0.42) | GDAACHESLC6A5MAPTTYRO3 | |
| SCHEMBL19153464 | 0.71 | SLC6A5 (0.41) | GDAACHESLC6A5MAPTERAP1 | |
| SCHEMBL6746072 | 0.71 | LRRK2 (0.44) | GDAACHESLC6A5MAPTAURKA | |
| SCHEMBL10217112 | 0.71 | FFAR2 (0.40) | GDAACHESLC6A5MAPTTYRO3 | |
| SCHEMBL2398078 | 0.71 | SLC6A5 (0.44) | GDAACHESLC6A5MAPTTYRO3 | |
| SCHEMBL31268389 | 0.71 | LRRK2 (0.44) | GDAACHESLC6A5MAPTAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |