Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12780767 | 0.95 | HSD11B1 (0.40) | ESR1ESR2HSD11B1ELANEPTPN1 | |
| SCHEMBL12558334 | 0.90 | HSD11B1 (0.54) | HSD11B1PTPN1PKMGAAPOLB | |
| SCHEMBL13818318 | 0.87 | HSD11B1 (0.35) | ESR1ESR2HSD11B1ELANEPTPN1 | |
| SCHEMBL16281209 | 0.85 | HSD11B1 (0.54) | HSD11B1PKMGAAPOLBL3MBTL1 | |
| SCHEMBL14288322 | 0.85 | ESR1 (0.56) | ESR1ESR2HSD11B1ELANEPTPN1 | |
| SCHEMBL12736452 | 0.85 | HSD11B1 (0.51) | HSD11B1PTPN1PKMGAAL3MBTL1 | |
| SCHEMBL12780726 | 0.84 | PKM (0.45) | ESR1ESR2ELANEPTPN1PKM | |
| SCHEMBL17169216 | 0.84 | HSD11B1 (0.46) | HSD11B1POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL17172537 | 0.84 | HSD11B1 (0.44) | HSD11B1PTPN1PKMPOLBL3MBTL1 | |
| SCHEMBL12736439 | 0.83 | HSD11B1 (0.44) | HSD11B1PTPN1PKMPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065021-A1 | Novel Sulfonic-Acid-Group-Containing Segmented Block Copolymer, Application Thereof, and Method of Manufacturing Novel Block Copolymer | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2011-03-17 | — | — | US | disclosed |