Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10296813 | 0.92 | HSD11B1 (0.34) | HSD11B1SLC6A4SLC6A3PTPN1HSD17B10 | |
| SCHEMBL14545945 | 0.92 | HSD11B1 (0.34) | HSD11B1SLC6A4SLC6A3PTPN1HSD17B10 | |
| SCHEMBL12780732 | 0.87 | ESR1 (0.41) | HSD11B1ELANEESR1ESR2GAA | |
| SCHEMBL12780767 | 0.84 | HSD11B1 (0.40) | HSD11B1ELANEESR1ESR2GAA | |
| SCHEMBL13919843 | 0.84 | SCN9A (0.31) | SCN9A | |
| SCHEMBL14545946 | 0.84 | HSD11B1 (0.34) | HSD11B1SLC6A4SLC6A3PTPN1HSD17B10 | |
| SCHEMBL13181478 | 0.83 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL13818319 | 0.80 | MMP3 (0.36) | PKMHSD17B10KDM4EALDH1A1POLB | |
| SCHEMBL12558334 | 0.80 | HSD11B1 (0.54) | HSD11B1GAAPKMPTPN1KDM4E | |
| SCHEMBL14557897 | 0.78 | HSD11B1 (0.31) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669391-B1 | BLOCK COPOLYMERS AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2009-06-03 | — | — | EP | disclosed |