Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17689576 | 0.90 | TSHR (0.39) | TSHRLMNAPOLBALDH1A1RECQL | |
| SCHEMBL22174072 | 0.87 | TSHR (0.52) | TSHRLMNAPOLBRECQLCASP2 | |
| SCHEMBL16411943 | 0.81 | EPHX1 (0.39) | TSHRALDH1A1MTNR1AMTNR1B | |
| SCHEMBL18164189 | 0.81 | TSHR (0.55) | TSHRPOLBRECQLCASP2NAAA | |
| SCHEMBL2616751 | 0.81 | TSHR (0.46) | TSHRLMNAPOLBCASP2 | |
| SCHEMBL19912223 | 0.80 | CASP2 (0.61) | ALDH1A1CASP2NAAA | |
| SCHEMBL6037110 | 0.79 | TSHR (0.40) | TSHRLMNAPOLBALDH1A1RECQL | |
| SCHEMBL5916650 | 0.79 | EPHX1 (0.48) | TSHRMTNR1AMTNR1B | |
| SCHEMBL20954114 | 0.79 | CYP2D6 (0.36) | TSHR | |
| SCHEMBL31565700 | 0.79 | KDM4E (0.48) | TSHRALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315714-B2 | Degradable non-aqueous gel systems | M-I L.L.C. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20110053809-A1 | DEGRADABLE NON-AQUEOUS GEL SYSTEMS | M-I L.L.C. (US) | 2011-03-03 | — | — | US | disclosed |
| US-20100120944-A1 | USE OF CURABLE LIQUID ELASTOMERS TO PRODUCE GELS FOR TREATING A WELLBORE | M-I L.L.C. (US) | 2010-05-13 | — | — | US | disclosed |