Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27628884 | 0.89 | TSHR (0.46) | TSHRPOLBRECQLSLC6A5CASP2 | |
| SCHEMBL12190502 | 0.86 | PAOX (0.50) | TSHRPOLBLMNASLC6A5CASP2 | |
| SCHEMBL12786199 | 0.79 | TSHR (0.45) | TSHRPOLBALDH1A1RECQLLMNA | |
| SCHEMBL553701 | 0.78 | CTSD (0.48) | TSHRPOLBALDH1A1RECQLLMNA | |
| SCHEMBL12190494 | 0.78 | SLC6A5 (0.52) | TSHRRECQLLMNASLC6A5CYP3A4 | |
| SCHEMBL27514494 | 0.77 | TSHR (0.44) | TSHRPOLBRECQLSLC6A5CASP2 | |
| SCHEMBL10481580 | 0.77 | CASP2 (0.65) | ALDH1A1CASP2 | |
| SCHEMBL38654455 | 0.76 | ALDH1A1 (0.42) | TSHRALDH1A1LMNASLC6A5CYP3A4 | |
| SCHEMBL22174072 | 0.76 | TSHR (0.52) | TSHRPOLBRECQLLMNACASP2 | |
| SCHEMBL16938668 | 0.76 | ALDH1A1 (0.36) | TSHRALDH1A1LMNASLC6A5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695076-A2 | REACTIVE OXYGEN DETECTING AND/OR ABSORBING COMPOUND, METHOD FOR PREPARING SAID COMPOUND AND A DEVICE COMPRISING IT | Universite Rennes 1 (FR) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005062038-A2 | REACTIVE OXYGEN DETECTING AND/OR ABSORBING COMPOUND, METHOD FOR PREPARING SAID COMPOUND AND A DEVICE COMPRISING IT | UNIVERSITE DE RENNES 1 (FR) | 2005-07-07 | — | — | WO | disclosed |