Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 5/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14665416 | 0.83 | AHR (0.42) | AHRNOTUMHTR5AHTR7ADRA2A | |
| SCHEMBL13806433 | 0.81 | BRD4 (0.71) | AHRBRD4CREBBPAKR1B1CMA1 | |
| SCHEMBL13885026 | 0.81 | AHR (0.51) | AHRNOTUMHTR5AHTR7ADRA2A | |
| SCHEMBL1700420 | 0.79 | AHR (0.43) | AHRNOTUMDRD4HTR2CHTR2B | |
| SCHEMBL12788177 | 0.78 | DRD1 (0.54) | BRD4NOTUMDRD4 | |
| SCHEMBL22335117 | 0.77 | AHR (0.44) | AHRNOTUMHTR5AHTR7ADRA2A | |
| SCHEMBL2606232 | 0.76 | BRD4 (0.68) | AHRBRD4CREBBPDRD4HTR2A | |
| SCHEMBL13068353 | 0.75 | CRHR1 (0.43) | AHRNOTUMHTR7CMA1SCN9A | |
| SCHEMBL14698684 | 0.74 | AHR (0.59) | AHRHTR5AHTR7ADRA2AADRA2B | |
| SCHEMBL1764573 | 0.74 | AHR (0.70) | AHRCMA1SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059954-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059954-A1 | CGRP ANTAGONISTS | CALCRL, CALCR, CALCA | AHR 2751/4885BRD4 3250/4885CREBBP 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.