SCHEMBL12792240

SCHEMBL12792240

c1ccc(-c2ccc3nc(-n4c5ccc6ccccc6c5c5ccc6c7c8ccccc8ccc7n(-c7ccccc7)c6c54)ccc3n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 4/20 0.39
HPGD P15428 3/20 0.39
PTGES O14684 2/20 0.35
NPC1 O15118 7/20 0.34
RAB9A P51151 6/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
LMNA P02545 2/20 0.34
RECQL P46063 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TDO2 P48775 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
NQO2 P16083 1/20 0.33
GAA P10253 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12131963 0.84 L3MBTL1 (0.42) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL15832256 0.84 CYP3A4 (0.43) MAPTALDH1A1KDM4EHPGDNPC1
SCHEMBL18926307 0.83 L3MBTL1 (0.37) MAPTALDH1A1KDM4ENPC1LMNA
SCHEMBL22199815 0.81 L3MBTL1 (0.38) MAPTALDH1A1KDM4ENPC1LMNA
SCHEMBL13789874 0.80 L3MBTL1 (0.44) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL22199813 0.79 L3MBTL1 (0.36) MAPTALDH1A1KDM4EPTGESL3MBTL1
SCHEMBL15450035 0.77 MAPT (0.39) MAPTALDH1A1KDM4EHPGDPTGES
SCHEMBL27452267 0.77 KDM4E (0.35) MAPTALDH1A1KDM4EHPGDPTGES
SCHEMBL17989924 0.77 KDM4E (0.36) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL22141765 0.76 ALDH1A1 (0.37) MAPTALDH1A1KDM4EHPGDPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2284920-B1 COMPOUND FOR ORGANIC ELECTRIC FIELD LIGHT-EMITTING ELEMENT AND ORGANIC ELECTRIC FIELD LIGHT-EMITTING ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2015-07-29 EP disclosed
US-8795848-B2 Indolocarbazole derivative with fused heterocyclic aromatic group for organic electroluminescent device and organic electroluminescent device containing same NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-08-05 US disclosed
US-8795848-B2 Indolocarbazole derivative with fused heterocyclic aromatic group for organic electroluminescent device and organic electroluminescent device containing same NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-08-05 US disclosed
US-20110062429-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-03-17 US disclosed
US-20110062429-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110062429-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE ARL1, LAS1L, MCOLN3 MAPT 2153/4885ALDH1A1 528/4885KDM4E 3677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.