SCHEMBL12131963

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12792229	0.89	KDM4E (0.50)	L3MBTL1KDM4EATMKMT2AIL1R1
	SCHEMBL22199815	0.89	L3MBTL1 (0.38)	L3MBTL1KDM4EATMTDO2KMT2A
	SCHEMBL18926307	0.88	L3MBTL1 (0.37)	L3MBTL1KDM4EATMTDO2KMT2A
	SCHEMBL22199813	0.86	L3MBTL1 (0.36)	L3MBTL1KDM4EATMTDO2KMT2A
	SCHEMBL12036280	0.85	L3MBTL1 (0.46)	L3MBTL1KDM4EATMKMT2AIL1R1
	SCHEMBL12792240	0.84	MAPT (0.39)	L3MBTL1KDM4ETDO2KMT2AMEN1
	SCHEMBL12133214	0.84	KDM4E (0.32)	L3MBTL1KDM4EATM
	SCHEMBL19849176	0.83	L3MBTL1 (0.44)	L3MBTL1KDM4EATMKMT2AIL1R1
	SCHEMBL10061802	0.83	L3MBTL1 (0.44)	L3MBTL1KDM4EATMKMT2AIL1R1
	SCHEMBL15073986	0.83	L3MBTL1 (0.46)	L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.