Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ATR | Q13535 | 3/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5291484 | 0.78 | KDM4E (0.58) | KDM4EALOX15L3MBTL1MAPTALDH1A1 | |
| SCHEMBL11887634 | 0.78 | KDM4E (0.58) | KDM4EALOX15L3MBTL1MAPTALDH1A1 | |
| SCHEMBL28348601 | 0.77 | P4HTM (0.58) | KDM4EALOX15L3MBTL1MAPTALDH1A1 | |
| SCHEMBL12793399 | 0.76 | NPC1 (0.70) | L3MBTL1MAPTALDH1A1KMT2ATSHR | |
| SCHEMBL19392276 | 0.76 | KDM4E (0.56) | KDM4EALOX15L3MBTL1MAPTALDH1A1 | |
| SCHEMBL28982334 | 0.75 | RAB9A (0.69) | KDM4EL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL11732738 | 0.75 | CA1 (0.60) | KDM4EMAPTKMT2ATGM2 | |
| SCHEMBL4710352 | 0.75 | KDM4E (0.54) | KDM4EALOX15L3MBTL1MAPTALDH1A1 | |
| SCHEMBL15408951 | 0.75 | NPC1 (0.74) | KDM4EMAPT | |
| SCHEMBL4884927 | 0.75 | KDM4E (0.54) | KDM4EALOX15L3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722742-B2 | Chemical compounds having antiviral activity against Dengue virus and other Flaviviruses | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2014-05-13 | — | — | US | disclosed |
| US-20110065686-A1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065686-A1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | MAVS, EIF2AK2, ZC3HAV1 | KDM4E 1167/4885ALOX15 3190/4885L3MBTL1 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.