Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710352 | 0.85 | KDM4E (0.54) | KDM4EALOX15L3MBTL1ALDH1A1MAPT | |
| SCHEMBL4709744 | 0.82 | PRKCI (0.43) | KDM4EALOX15L3MBTL1ALDH1A1MAPT | |
| SCHEMBL11887634 | 0.80 | KDM4E (0.58) | KDM4EALOX15L3MBTL1ALDH1A1MAPT | |
| SCHEMBL5291484 | 0.80 | KDM4E (0.58) | KDM4EALOX15L3MBTL1ALDH1A1MAPT | |
| SCHEMBL19392276 | 0.77 | KDM4E (0.56) | KDM4EALOX15L3MBTL1ALDH1A1MAPT | |
| SCHEMBL3915690 | 0.76 | MAPT (0.66) | KDM4EALOX15L3MBTL1ALDH1A1MAPT | |
| SCHEMBL12793752 | 0.75 | KDM4E (0.56) | KDM4EALOX15L3MBTL1ALDH1A1MAPT | |
| SCHEMBL28348601 | 0.75 | P4HTM (0.58) | KDM4EALOX15L3MBTL1ALDH1A1MAPT | |
| SCHEMBL8256205 | 0.74 | RET (0.40) | ALDH1A1MAPTATRATMPRKCI | |
| SCHEMBL4312329 | 0.73 | NPC1 (0.57) | KDM4EALOX15L3MBTL1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214533-A1 | Cyclic Iminocarbamates And Their Use | BAYER HEALTHCARE AG (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20080214533-A1 | Cyclic Iminocarbamates And Their Use | BAYER HEALTHCARE AG (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20080214533-A1 | Cyclic Iminocarbamates And Their Use | BAYER HEALTHCARE AG (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20060287315-A1 | Pyrazinedicarboxamides and their use | BAYER HEALTHCARE AG (DE) | 2006-12-21 | — | — | US | disclosed |
| WO-2006061116-A1 | PYRAZINE DICARBOXAMIDES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-06-15 | — | — | WO | disclosed |
| WO-2006058630-A1 | CYCLIC IMINOCARBAMATES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287315-A1 | Pyrazinedicarboxamides and their use | PEPD, AADAC, PYCARD | KDM4E 1426/4885ALOX15 1615/4885L3MBTL1 4687/4885 |
| US-20080214533-A1 | Cyclic Iminocarbamates And Their Use | F2, UQCRB, F12 | KDM4E 3856/4885ALOX15 880/4885L3MBTL1 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.