Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871442 | 0.86 | MAPT (0.52) | MAPTPOLBPKMLMNAPTGS2 | |
| SCHEMBL1770323 | 0.84 | POLB (0.56) | MAPTPOLBPKMLMNAKMT2A | |
| SCHEMBL9343618 | 0.83 | PKM (1.00) | MAPTPOLBPKMLMNAPTGS2 | |
| SCHEMBL14024262 | 0.83 | MAPT (0.77) | MAPTPOLBPKMLMNAPTGS2 | |
| SCHEMBL31729674 | 0.82 | ELANE (0.53) | MAPTPOLBPKMLMNAPTGS2 | |
| SCHEMBL1930857 | 0.82 | MAPT (0.74) | MAPTPOLBPKMLMNAPTGS2 | |
| SCHEMBL3161812 | 0.82 | MAPT (0.74) | MAPTPOLBPKMLMNAPTGS2 | |
| SCHEMBL3291980 | 0.82 | PKM (0.47) | MAPTPOLBPKMPTGS2KMT2A | |
| SCHEMBL1770600 | 0.81 | POLB (0.53) | MAPTPOLBPKMLMNAKMT2A | |
| SCHEMBL65266 | 0.80 | MAPT (0.71) | MAPTPOLBPKMLMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777061-A | Epoxy functionalized lithium sulfonyl imide and preparation method and application thereof | 上海交通大学绍兴新能源与分子工程研究院 | 2024-03-29 | — | — | CN | claimed |
| EP-0391652-B1 | Interphenylène 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasopastic disease | SQUIBB & SONS INC (US) | 1995-03-15 | — | — | EP | claimed |
| US-20240425450-A1 | SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS | Artizan Biosciences, Inc. | 2024-12-26 | — | — | US | disclosed |
| WO-2024147287-A1 | ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR PRODUCING ELECTRONIC DEVICE | 富士フイルム株式会社 | 2024-07-11 | — | — | WO | disclosed |
| CN-117777061-A | Epoxy functionalized lithium sulfonyl imide and preparation method and application thereof | 上海交通大学绍兴新能源与分子工程研究院 | 2024-03-29 | — | — | CN | disclosed |
| US-20230357139-A1 | SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS | Artizan Biosciences, Inc. | 2023-11-09 | — | — | US | disclosed |
| US-20230357139-A1 | SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS | Artizan Biosciences, Inc. | 2023-11-09 | — | — | US | disclosed |
| US-20230357139-A1 | SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS | Artizan Biosciences, Inc. | 2023-11-09 | — | — | US | disclosed |
| EP-4210738-A2 | SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS | Artizan Biosciences, Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| CN-109153642-B | Indole and azaindole halogenated allylamine derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2022-05-17 | — | — | CN | disclosed |
| WO-2022056369-A2 | SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS | Artizan Biosciences, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |
| EP-0453960-A1 | Sulfonylamino substituted bicyclyl hydroxamic acid derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4916231-A | THROMBOXANE A2 RECPTOR ANTAGONISTS | SHIONOGI & CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| US-4904819-A | ANTICOAGULANTS, VASODILATORS, BRONCHODILATORS; SALT FORMATION, HYDROLYSIS, ESTERIFICATION | SHIONOGI & CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0352083-A2 | Alkenyltetrazole derivatives, their preparation and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |
| EP-0199672-B1 | OXIME SULPHONATES CONTAINING REACTIVE GROUPS | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | disclosed |
| US-4736055-A | STARING MATERIAL FOR PHOTORESIST POLYMERS | CIBA-GEIGY CORPORATION (US) | 1988-04-05 | — | — | US | disclosed |
| EP-0199672-A1 | Oxime sulphonates containing reactive groups | CIBA-GEIGY AG (CH) | 1986-10-29 | — | — | EP | disclosed |
| US-4443536-A | CONTAINING BALLAST WITH HYDROXYPHENYLSULFINYL OR HYDROXYPHENYLSULFONYL GROUP | EASTMAN KODAK COMPANY (US) | 1984-04-17 | — | — | US | disclosed |
| EP-0073636-A1 | Photographic elements containing ballasted couplers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357139-A1 | SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS | FABP2, APC, SI | MAPT 4222/4885POLB 604/4885PKM 3645/4885 |
| US-20240425450-A1 | SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS | FABP2, APC, SI | MAPT 4222/4885POLB 604/4885PKM 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.