Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 5/20 | 0.38 |
| ▸ | TYK2 | P29597 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12795370 | 0.84 | ROCK2 (0.56) | ROCK2ROCK1JAK2TYK2ALDH1A1 | |
| SCHEMBL1666240 | 0.78 | DHODH (0.50) | ROCK2ROCK1JAK2TYK2JAK1 | |
| SCHEMBL1665438 | 0.75 | DHODH (0.56) | ALDH1A1LMNARAB9ATDP1KDM4E | |
| SCHEMBL4063435 | 0.71 | ITGB1 (0.55) | JAK2TYK2JAK1ITGB1ITGA4 | |
| SCHEMBL5755776 | 0.69 | JAK2 (0.68) | ROCK2ROCK1JAK2TYK2ALDH1A1 | |
| SCHEMBL826357 | 0.68 | MKNK1 (0.58) | ROCK2ROCK1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28637331 | 0.67 | MKNK1 (0.57) | ROCK2ROCK1ALDH1A1MEN1KMT2A | |
| SCHEMBL30679654 | 0.66 | GSK3B (0.43) | ROCK2ALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL21925661 | 0.66 | RAD52 (0.54) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL28072777 | 0.66 | JAK2 (0.67) | ROCK2ROCK1JAK2TYK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043404-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-14 | — | — | WO | disclosed |