Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | ATF1 | P18846 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665446 | 0.83 | JAK2 (0.67) | DHODHJAK2JAK1TYK2EPHX2 | |
| SCHEMBL1665438 | 0.83 | DHODH (0.56) | DHODHEPHX2TDO2LMNAMAPT | |
| SCHEMBL12795428 | 0.78 | ROCK2 (0.41) | JAK2JAK1TYK2LMNAMAPT | |
| SCHEMBL1666242 | 0.76 | ALDH1A1 (0.54) | TRPV1LMNAMAPTMAPK1KMT2A | |
| SCHEMBL4749048 | 0.71 | CES2 (0.56) | JAK2JAK1TYK2KIF11EPHX2 | |
| SCHEMBL1665440 | 0.70 | HSD17B13 (0.45) | NAMPTLMNAMAPT | |
| SCHEMBL3924091 | 0.69 | JAK2 (0.56) | DHODHJAK2JAK1TYK2EPHX2 | |
| SCHEMBL8484731 | 0.69 | DHODH (0.71) | DHODHKIF11EPHX2LMNAKMT2A | |
| SCHEMBL4691580 | 0.69 | PIK3CA (0.52) | JAK2JAK1TYK2NAMPTTRPV1 | |
| SCHEMBL20560147 | 0.68 | KIF11 (0.59) | KIF11EPHX2TRPV1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486035-B1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL CO (JP) | 2015-08-26 | — | — | EP | disclosed |
| EP-2486035-B1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL CO (JP) | 2015-08-26 | — | — | EP | disclosed |
| US-8742112-B2 | Heterocyclic compound and its use for control of an arthropod pest | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-06-03 | — | — | US | disclosed |
| US-8742112-B2 | Heterocyclic compound and its use for control of an arthropod pest | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-06-03 | — | — | US | disclosed |
| EP-2486035-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | Sumitomo Chemical Co., Ltd (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20120196891-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120196891-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-02 | — | — | US | disclosed |
| WO-2011043404-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011043404-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196891-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | HAAO, DDT, ACHE | DHODH 279/4885JAK2 3044/4885JAK1 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.