Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17188854 | 0.94 | TSHR (0.42) | FFAR4FFAR1LMNAALDH1A1GSTK1 | |
| SCHEMBL1752252 | 0.85 | GABRP (0.48) | LMNATSHRENPEP | |
| SCHEMBL1751466 | 0.85 | GABRP (0.48) | LMNATSHRENPEP | |
| SCHEMBL1752703 | 0.85 | GABRP (0.48) | LMNATSHRENPEP | |
| SCHEMBL11559068 | 0.83 | TSHR (0.46) | LMNAALDH1A1GSTK1TSHRNFKB1 | |
| SCHEMBL12743238 | 0.81 | TSHR (0.47) | FFAR4FFAR1ALDH1A1TSHRAKR1B1 | |
| SCHEMBL2725090 | 0.76 | BLM (0.52) | — | |
| SCHEMBL25639990 | 0.76 | ALDH1A1 (0.51) | FFAR4FFAR1ALDH1A1GSTK1TSHR | |
| SCHEMBL9405817 | 0.73 | LMNA (0.58) | FFAR4FFAR1LMNAALDH1A1GSTK1 | |
| SCHEMBL245252 | 0.73 | KDM4C (0.60) | FFAR4FFAR1LMNAALDH1A1GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044138-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2011-04-14 | — | — | WO | disclosed |