Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305616 | 0.82 | KDM4E (0.64) | RAD52USP2KDM4ECHEK1ALDH1A1 | |
| SCHEMBL23133806 | 0.82 | DRD2 (0.54) | RAD52KDM4EALDH1A1OPRM1 | |
| Hydrochloric Acid SCHEMBL4652172 | 0.80 | KDM4E (0.62) | RAD52USP2KDM4ECHEK1ALDH1A1 | |
| SCHEMBL27457690 | 0.78 | RAD52 (0.61) | RAD52USP2KDM4EALDH1A1MAPT | |
| SCHEMBL17737082 | 0.78 | KDM4E (0.71) | USP2KDM4ECHEK1ALDH1A1MAPT | |
| SCHEMBL23610369 | 0.78 | KDM4E (0.71) | USP2KDM4ECHEK1ALDH1A1MAPT | |
| SCHEMBL4553749 | 0.77 | KDM4E (0.57) | RAD52USP2KDM4ECHEK1ALDH1A1 | |
| SCHEMBL1708824 | 0.76 | BCHE (0.47) | RAD52KDM4EMAPT | |
| SCHEMBL22751990 | 0.76 | CHKA (0.47) | RAD52KDM4EALDH1A1MAPTPKM | |
| SCHEMBL1305865 | 0.76 | DRD2 (0.65) | USP2KDM4ECHEK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8287969-B2 | Isosorbide derivatives and liquid crystal displays comprising the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-10-16 | — | — | US | disclosed |
| CN-102453037-A | Isosorbide derivative and liquid crystal display comprising the same | IND TECH RES INST | 2012-05-16 | — | — | CN | disclosed |
| US-20120086902-A1 | ISOSORBIDE DERIVATIVES AND LIQUID CRYSTAL DISPLAYS COMPRISING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120086902-A1 | ISOSORBIDE DERIVATIVES AND LIQUID CRYSTAL DISPLAYS COMPRISING THE SAME | CX3CR1, CBX3, YBX3 | RAD52 3660/4885USP2 3415/4885KDM4E 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.