Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | FUT4 | P22083 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12800168 | 0.82 | CYP3A4 (0.52) | HPGDCA9ALDH1A1LMNAMAPK1 | |
| SCHEMBL1672199 | 0.82 | SELL (0.39) | MAPTHPGDKDM4ESELLSELP | |
| Torachrysone SCHEMBL29380720 | 0.77 | CYP3A4 (0.51) | MAPTHPGDKDM4EALDH1A1MAPK1 | |
| Torachrysone SCHEMBL932035 | 0.77 | CYP3A4 (0.51) | MAPTHPGDKDM4EALDH1A1MAPK1 | |
| SCHEMBL20020395 | 0.76 | CA12 (0.42) | MAPTHPGDCA12CA1CA2 | |
| SCHEMBL29914372 | 0.75 | CA12 (0.61) | MAPTHPGDCA12CA1CA2 | |
| SCHEMBL686591 | 0.75 | CA12 (0.61) | MAPTHPGDCA12CA1CA2 | |
| Nepodin SCHEMBL1673268 | 0.74 | MEN1 (0.53) | MAPTHPGDKDM4EALDH1A1TP53 | |
| Nepodin SCHEMBL30189621 | 0.74 | MEN1 (0.53) | MAPTHPGDKDM4EALDH1A1TP53 | |
| SCHEMBL16418737 | 0.73 | TPMT (0.52) | MAPTHPGDCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488152-B1 | COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION | OREAL (FR) | 2018-04-04 | — | — | EP | claimed |
| US-8551189-B2 | Composition comprising at least one 1,8-dihydroxynaphthalene derivative and at least one basifying agent different from aqueous ammonia, process for dyeing keratin fibres using the composition | L'OREAL (FR) | 2013-10-08 | — | — | US | claimed |
| EP-2488152-B1 | COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION | OREAL (FR) | 2018-04-04 | — | — | EP | disclosed |
| EP-2488152-B1 | COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION | OREAL (FR) | 2018-04-04 | — | — | EP | disclosed |
| US-8551189-B2 | Composition comprising at least one 1,8-dihydroxynaphthalene derivative and at least one basifying agent different from aqueous ammonia, process for dyeing keratin fibres using the composition | L'OREAL (FR) | 2013-10-08 | — | — | US | disclosed |
| US-8551189-B2 | Composition comprising at least one 1,8-dihydroxynaphthalene derivative and at least one basifying agent different from aqueous ammonia, process for dyeing keratin fibres using the composition | L'OREAL (FR) | 2013-10-08 | — | — | US | disclosed |
| US-8551189-B2 | Composition comprising at least one 1,8-dihydroxynaphthalene derivative and at least one basifying agent different from aqueous ammonia, process for dyeing keratin fibres using the composition | L'OREAL (FR) | 2013-10-08 | — | — | US | disclosed |
| US-20130219633-A1 | COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION | L'OREAL (FR) | 2013-08-29 | — | — | US | disclosed |
| US-20130219633-A1 | COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION | L'OREAL (FR) | 2013-08-29 | — | — | US | disclosed |
| WO-2012136782-A1 | METHOD OF DYEING OR MAKING UP KERATIN FIBRES USING A PIGMENT RESULTING FROM A 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE, COMPOSITION CONTAINING THE PIGMENT AND THE PIGMENT | L'OREAL (FR) | 2012-10-11 | — | — | WO | disclosed |
| WO-2011045403-A2 | COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION | L'OREAL (FR) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130219633-A1 | COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION | KRT18, DSG1, TUBA8 | MAPT 131/4885HPGD 1004/4885CA12 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.