TUBA8

Tubulin alpha-8 chain · Q9NY65 · TUBA8 on Sugi Atlas →

23 patent compounds predicted against TUBA8, 4 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Pironetin Pironetin (SCHEMBL8940434) 1.00 2/20
Pironetin Pironetin (SCHEMBL8940436) 1.00 2/20
Pironetin Pironetin (SCHEMBL9305413) 1.00 2/20
SCHEMBL12632514 SCHEMBL12632514 0.77 2/20

Clinical trials — most relevant to TUBA8 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparative Analysis of the Efficacies in Neoadjuvant Chemotherapy of Breast Cancer PHASE3COMPLETED
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer PHASE2UNKNOWN
Biologic Correlative Taxotere/AC PHASE2COMPLETED
Neoadjuvant Paclitaxel Plus Epirubicin Versus Vinorelbine Plus Epirubicin in Breast Cancer With TEKT4 Variations PHASE2COMPLETED
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer PHASE2COMPLETED
A Multicenter Study of NAP (AL-108) in Schizophrenia PHASE2COMPLETED
Therapy With Docetaxel and ZD1839 for Patients Who Have Advanced Breast Cancer PHASE2COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies PHASE1COMPLETED
Exploratory Evaluation of [11C]MPC6827 EARLY_PHASE1COMPLETED
Epithelial Mesenchymal Transition and Periodontitis nanUNKNOWN
Diagnostic of Chemotherapy Induced Neuropathy in Children nanCOMPLETED
Prostate Cancer Antigen 3 (PCA-3) Gene Project nanCOMPLETED
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting nanUNKNOWN
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Effect of Low Dose of Colchicine on Platelet Reactivity nanCOMPLETED
Biomarkers in the Diagnosis and Prognosis of NAFLD nanRECRUITING
Myotubular Myopathy Genetic Testing Study nanCOMPLETED
Importance of the Microtubule Cytoskeleton in Oocyte Competence nanCOMPLETED
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
Evaluation of Possible Genes in Periodontal Diseases by Genetic Methods nanUNKNOWN
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
PCD New Gene Discovery nanCOMPLETED
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Thermal Spa Treatment and Improvement of Primary Ciliary Dyskinesia nanRECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Evaluation of a Novel PET Radioligand to Image OGA nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TUBA8 binder may also engage these)

ProteinNameSimilarity
Q6AY56 1.000 Q6AY56 →
P02552 1.000 P02552 →
P68369 1.000 P68369 →
Q2HJB8 1.000 Q2HJB8 →
TUBA4A Tubulin alpha-4A chain 1.000 landscape →
A5A6J1 1.000 A5A6J1 →
Q52PV9 1.000 Q52PV9 →
Q91060 1.000 Q91060 →
P0DPH8 1.000 P0DPH8 →
Q9JJZ2 1.000 Q9JJZ2 →
P06604 1.000 P06604 →
P68367 1.000 P68367 →
P18288 1.000 P18288 →
P68360 1.000 P68360 →
P68368 1.000 P68368 →
Q06331 1.000 Q06331 →
P34690 1.000 P34690 →
Q32KN8 1.000 Q32KN8 →
Q6AYZ1 1.000 Q6AYZ1 →
P68373 1.000 P68373 →
P02550 1.000 P02550 →
P50719 1.000 P50719 →
P91910 1.000 P91910 →
Q94572 1.000 Q94572 →
P68370 1.000 P68370 →
P68361 1.000 P68361 →
P09644 1.000 P09644 →
Q5XIF6 1.000 Q5XIF6 →
P06606 1.000 P06606 →
Q5R1W4 1.000 Q5R1W4 →