Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18711704 | 0.85 | ITGB3 (0.41) | MEN1KMT2AGAAITGB3ITGA2B | |
| SCHEMBL12800856 | 0.83 | ITGB3 (0.40) | MEN1KMT2AGAAITGB3ITGA2B | |
| SCHEMBL17320501 | 0.83 | ITGB3 (0.40) | MEN1KMT2AGAAITGB3ITGA2B | |
| SCHEMBL12522241 | 0.83 | HPGD (0.44) | HPGDMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL12448263 | 0.80 | HPGD (0.42) | HPGDMEN1KMT2AGAAITGB3 | |
| SCHEMBL7906646 | 0.80 | HPGD (0.44) | HPGDMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11989435 | 0.78 | ALDH1A1 (0.61) | HPGDMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL28851673 | 0.77 | GAA (0.42) | GAAITGB3ITGA2BALDH1A1MAPT | |
| SCHEMBL13359380 | 0.76 | HPGD (0.41) | HPGDMEN1KMT2AALDH1A1APOBEC3A | |
| SCHEMBL26793098 | 0.76 | HPGD (0.44) | HPGDMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046970-A1 | AMINO - PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBKL AND/OR IKK EPSILON | MYREXIS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |