Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12800856 | 1.00 | ITGB3 (0.40) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL17320503 | 0.90 | DPP4 (0.40) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL18711704 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL12800960 | 0.83 | HPGD (0.40) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL12800958 | 0.81 | ITGB3 (0.38) | ITGB3ITGA2BALDH1A1EPHX2GAA | |
| SCHEMBL10328343 | 0.80 | KMT2A (0.43) | MEN1KMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL12521996 | 0.80 | KMT2A (0.43) | MEN1KMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL28851673 | 0.80 | GAA (0.42) | ITGB3ITGA2BALDH1A1MAPTGAA | |
| SCHEMBL10328208 | 0.79 | ALDH1A1 (0.42) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL20929383 | 0.79 | ALDH1A1 (0.42) | ITGB3ITGA2BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015187684-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2015-12-10 | — | — | WO | disclosed |