SCHEMBL12801014 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ERN1	O75460	2/20	0.41

▸	BRD4	O60885	14/20	0.39

▸	USP7	Q93009	1/20	0.39

▸	MLYCD	O95822	1/20	0.37

▸	BRD2	P25440	2/20	0.36

▸	BRD3	Q15059	1/20	0.36

▸	JAK2	O60674	1/20	0.35

▸	FFAR1	O14842	1/20	0.35

▸	CREBBP	Q92793	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1670622	0.84	ERN1 (0.39)	ERN1BRD4MLYCDBRD2FFAR1
SCHEMBL1672894	0.84	ERN1 (0.38)	ERN1BRD4USP7MLYCDBRD2
SCHEMBL1672896	0.84	ERN1 (0.38)	ERN1BRD4USP7MLYCDBRD2
SCHEMBL1672899	0.82	ERN1 (0.38)	ERN1BRD4MLYCDFFAR1CREBBP
SCHEMBL12800382	0.78	MLYCD (0.42)	ERN1BRD4MLYCDBRD2BRD3
SCHEMBL12801015	0.77	MLYCD (0.45)	ERN1BRD4USP7MLYCDBRD2
SCHEMBL12801001	0.74	BRD4 (0.39)	ERN1BRD4MLYCDBRD2BRD3
SCHEMBL12800390	0.72	BRD4 (0.43)	ERN1BRD4USP7MLYCDBRD2
SCHEMBL12362813	0.71	BRD4 (0.66)	ERN1BRD4MLYCDBRD2CREBBP
SCHEMBL12808114	0.70	BRD4 (0.45)	ERN1BRD4MLYCDBRD2BRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011042477-A1	SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS	KARO BIO AB (SE)	2011-04-14	—	—	WO	disclosed