Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 14/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672896 | 1.00 | ERN1 (0.38) | ERN1BRD4USP7MLYCDCREBBP | |
| SCHEMBL12801014 | 0.84 | ERN1 (0.41) | ERN1BRD4USP7MLYCDCREBBP | |
| SCHEMBL1672899 | 0.83 | ERN1 (0.38) | ERN1BRD4MLYCDCREBBPFFAR1 | |
| SCHEMBL1671312 | 0.83 | BRD4 (0.42) | BRD4MLYCDCREBBPBRD2 | |
| SCHEMBL1671314 | 0.83 | BRD4 (0.42) | BRD4MLYCDCREBBPBRD2 | |
| SCHEMBL1670732 | 0.81 | MLYCD (0.38) | ERN1BRD4MLYCDCREBBPBRD2 | |
| SCHEMBL1670734 | 0.81 | MLYCD (0.38) | ERN1BRD4MLYCDCREBBPBRD2 | |
| SCHEMBL1670622 | 0.79 | ERN1 (0.39) | ERN1BRD4MLYCDCREBBPFFAR1 | |
| SCHEMBL1670526 | 0.79 | BRD4 (0.36) | ERN1BRD4MLYCDCREBBPBRD2 | |
| SCHEMBL1670528 | 0.79 | BRD4 (0.36) | ERN1BRD4MLYCDCREBBPBRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |