Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668562 | 0.91 | TPSAB1 (0.58) | TPSAB1PRSS1TPSD1TPSG1KDM4E | |
| SCHEMBL1668508 | 0.86 | PREP (0.52) | TPSAB1PRSS1TPSD1TPSG1KDM4E | |
| SCHEMBL1668952 | 0.85 | SIGMAR1 (0.58) | TPSAB1PRSS1TPSD1TPSG1KDM4E | |
| SCHEMBL11263011 | 0.85 | PREP (0.59) | PREPNPSR1MEN1KMT2A | |
| SCHEMBL7159251 | 0.85 | PREP (0.59) | PREPNPSR1MEN1KMT2A | |
| SCHEMBL1670890 | 0.85 | KDM4E (0.50) | TPSAB1PRSS1TPSD1TPSG1KDM4E | |
| SCHEMBL27795955 | 0.81 | PREP (0.56) | PREPNPSR1MEN1KMT2A | |
| SCHEMBL29176117 | 0.81 | PLAU (0.68) | PPIDTPSAB1PRSS1TPSD1TPSG1 | |
| SCHEMBL3183198 | 0.81 | PLAU (0.68) | PPIDTPSAB1PRSS1TPSD1TPSG1 | |
| SCHEMBL8750837 | 0.80 | PREP (0.60) | PREPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |