Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955614 | 0.86 | L3MBTL1 (0.49) | SIGMAR1L3MBTL1MAPTPREPALDH1A1 | |
| SCHEMBL1668952 | 0.85 | SIGMAR1 (0.58) | KDM4EHRH3SIGMAR1TPSAB1PLAU | |
| SCHEMBL12801427 | 0.85 | PPID (0.53) | KDM4EHRH3TPSAB1PLAUPREP | |
| SCHEMBL1668562 | 0.85 | TPSAB1 (0.58) | KDM4EHRH3TPSAB1PLAUPREP | |
| SCHEMBL1668508 | 0.82 | PREP (0.52) | KDM4EHRH3TPSAB1PLAUPREP | |
| SCHEMBL952100 | 0.81 | ALDH1A1 (0.52) | PREPALDH1A1TSHR | |
| SCHEMBL11263011 | 0.80 | PREP (0.59) | SIGMAR1PKML3MBTL1PREPALDH1A1 | |
| SCHEMBL7159251 | 0.80 | PREP (0.59) | SIGMAR1PKML3MBTL1PREPALDH1A1 | |
| SCHEMBL3806762 | 0.78 | EPHX2 (0.56) | L3MBTL1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL2586953 | 0.78 | L3MBTL1 (0.61) | L3MBTL1MAPTPREPALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |