Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193995 | 0.83 | NFE2L2 (0.46) | NFE2L2IKBKBKCNH2MAT2ARAB9A | |
| SCHEMBL22288220 | 0.83 | ALDH1A1 (0.35) | TDP1 | |
| SCHEMBL829563 | 0.77 | ERN1 (0.42) | NFE2L2IKBKBKCNH2MAT2AABCG2 | |
| SCHEMBL27298431 | 0.77 | ALDH1A1 (0.34) | RAB9AHPGDKDM4ENPC1LMNA | |
| SCHEMBL10038011 | 0.74 | ALDH1A1 (0.39) | — | |
| SCHEMBL16933848 | 0.74 | NFE2L2 (0.50) | NFE2L2IKBKBKCNH2MAT2ARAB9A | |
| SCHEMBL23746786 | 0.73 | NFE2L2 (0.39) | NFE2L2IKBKBKCNH2MAT2ARAB9A | |
| SCHEMBL29700809 | 0.73 | HPGD (0.47) | KCNH2MAT2ARAB9AHPGDKDM4E | |
| SCHEMBL1986111 | 0.73 | MAOB (0.42) | NFE2L2IKBKBKCNH2MAT2ARAB9A | |
| SCHEMBL29947357 | 0.73 | MAOB (0.42) | NFE2L2IKBKBKCNH2MAT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007426-A1 | NOVEL STYRENE COMPOUNDS AND A PROCESS FOR THE PREPARATION THEREOF | PI INDUSTRIES LTD. (IN) | 2023-02-02 | — | — | WO | disclosed |
| WO-2011040510-A1 | INDAZOLE ANALOGUE | 旭化成ファーマ株式会社 (JP) | 2011-04-07 | — | — | WO | disclosed |