Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22652503 | 0.86 | HTR2C (0.57) | HTR2CSLC18A3SIGMAR1QDPRHTR6 | |
| SCHEMBL1668790 | 0.81 | HTR2C (0.51) | HTR2CSLC18A3SIGMAR1QDPR | |
| SCHEMBL22567480 | 0.80 | HTR2C (0.57) | HTR2CSLC18A3SIGMAR1QDPRHTR6 | |
| SCHEMBL7624146 | 0.80 | HTR2C (0.57) | HTR2CSLC18A3SIGMAR1QDPRHTR6 | |
| SCHEMBL4404411 | 0.80 | HTR2C (0.57) | HTR2CSLC18A3SIGMAR1QDPRHTR6 | |
| SCHEMBL4518387 | 0.80 | HTR2C (0.62) | HTR2CSLC18A3SIGMAR1QDPRHTR6 | |
| SCHEMBL7496895 | 0.79 | SLC18A3 (0.61) | HTR2CSLC18A3SIGMAR1QDPRHTR6 | |
| Hydrochloric Acid SCHEMBL30946017 | 0.79 | HTR2C (0.63) | HTR2CSLC18A3SIGMAR1QDPRHTR6 | |
| SCHEMBL8844193 | 0.77 | DRD2 (0.48) | HTR2C | |
| SCHEMBL14879996 | 0.77 | HTR2C (0.50) | HTR2CSLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, FTH1, HCCS | HTR2C 4174/4885SLC18A3 1331/4885SIGMAR1 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.