Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197780 | 0.92 | AGTR2 (0.40) | POLBAGTR2MAPTEGFRL3MBTL1 | |
| SCHEMBL4232692 | 0.85 | AGTR2 (0.36) | POLBAGTR2MAPTEGFRL3MBTL1 | |
| SCHEMBL4196535 | 0.76 | AGTR2 (0.40) | POLBAGTR2MAPTEGFRL3MBTL1 | |
| SCHEMBL18660067 | 0.74 | USP2 (0.41) | MAPTTSHRELANE | |
| SCHEMBL4196402 | 0.74 | ALDH1A1 (0.41) | MAPTMEN1KMT2ATSHR | |
| SCHEMBL18632628 | 0.73 | ALOX5 (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL4204607 | 0.72 | ACE (0.40) | POLBAGTR2EGFRMEN1KMT2A | |
| SCHEMBL4203532 | 0.71 | KDM4E (0.39) | POLBEGFR | |
| SCHEMBL4194407 | 0.71 | CYP19A1 (0.39) | EGFRL3MBTL1 | |
| SCHEMBL4199776 | 0.71 | KDM4E (0.37) | POLBL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041512-A2 | COMPOSITIONS AND METHODS FOR TREATING MLV-INFECTION, AND PREVENTING AND TREATING MLV-INITIATED DISEASES | EMORY UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |