Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501834 | 0.88 | LMNA (0.33) | RXRANR4A2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL12808402 | 0.76 | LMNA (0.35) | LMNAALDH1A1SMN1; SMN2POLBCYP2C9 | |
| SCHEMBL501301 | 0.76 | THRB (0.32) | — | |
| SCHEMBL501496 | 0.73 | MAPT (0.34) | KDM4EGAAMAPTHPGDKMT2A | |
| SCHEMBL501208 | 0.72 | NPC1 (0.32) | — | |
| SCHEMBL7759921 | 0.69 | NPSR1 (0.35) | LMNAALDH1A1SMN1; SMN2POLBCYP2C9 | |
| SCHEMBL501476 | 0.69 | CRHR1 (0.36) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL20564322 | 0.66 | CNR2 (0.43) | LMNAALDH1A1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL20563862 | 0.66 | GAA (0.33) | ALDH1A1GAATSHRTDP1 | |
| SCHEMBL10204359 | 0.65 | KDM4E (0.31) | NPSR1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041512-A2 | COMPOSITIONS AND METHODS FOR TREATING MLV-INFECTION, AND PREVENTING AND TREATING MLV-INITIATED DISEASES | EMORY UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |