Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | XDH | P47989 | 5/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697438 | 0.95 | ALDH1A1 (0.70) | ALDH1A1HPGDXDH | |
| SCHEMBL7697436 | 0.95 | ALDH1A1 (0.70) | ALDH1A1HPGDXDH | |
| Hydrochloric Acid SCHEMBL9650706 | 0.94 | ALDH1A1 (0.68) | ALDH1A1HPGDXDH | |
| SCHEMBL399653 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HPGDXDH | |
| SCHEMBL403582 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HPGDXDH | |
| SCHEMBL9651231 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HPGDXDHPDE4APDE4B | |
| SCHEMBL9649896 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HPGDXDH | |
| SCHEMBL9650699 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HPGDXDH | |
| SCHEMBL7692779 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGDXDHPDE4APDE4B | |
| SCHEMBL403398 | 0.81 | XDH (0.67) | ALDH1A1HPGDXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137181-B1 | OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE (S1P) AGONISTS | GLAXO GROUP LTD (GB) | 2011-03-02 | — | — | EP | disclosed |