SCHEMBL403398

SCHEMBL403398

CC(C)Oc1ccc(C(=O)O)cc1C#N

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
XDH P47989 8/20 0.67
ALDH1A1 P00352 1/20 0.58
HPGD P15428 1/20 0.58
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30603423 1.00 XDH (0.67) XDHALDH1A1HPGDKMT2A
Hydrochloric Acid SCHEMBL28477854 0.98 XDH (0.66) XDHALDH1A1HPGDKMT2A
SCHEMBL1872491 0.91 XDH (0.60) XDHALDH1A1HPGDKMT2A
SCHEMBL28323507 0.88 XDH (0.56) XDHALDH1A1KMT2A
SCHEMBL31470463 0.86 XDH (0.55) XDHALDH1A1HPGD
SCHEMBL1016450 0.86 XDH (0.55) XDHALDH1A1HPGD
SCHEMBL2103708 0.86 XDH (0.55) XDHALDH1A1HPGD
SCHEMBL403582 0.85 ALDH1A1 (0.60) XDHALDH1A1HPGD
SCHEMBL399653 0.85 ALDH1A1 (0.60) XDHALDH1A1HPGD
SCHEMBL1807138 0.85 XDH (0.54) XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12459907-B2 Process for the production of ozanimod EGIS GYOGYSZERGYAR ZRT. (HU) 2025-11-04 US claimed
EP-3630738-B1 PROCESS FOR THE PRODUCTION OF OZANIMOD EGYT GYOGYSZERVEGYESZETI GYAR (HU) 2023-07-19 EP claimed
CN-112062785-B Preparation method of ozagrel and intermediate thereof 广东东阳光药业有限公司 2023-06-27 CN claimed
US-20210108245-A1 Enantioselective Biocatalytic Preparation of 4-Cyano-Substituted 1-Aminoindane and Ozanimod PHARMAZELL GMBH (DE) 2021-04-15 US claimed
EP-3775253-A1 ENANTIOSELECTIVE BIOCATALYTIC PREPARATION OF 4-CYANO-SUBSTITUTED 1-AMINOINDANE AND OZANIMOD Pharmazell GmbH (DE) 2021-02-17 EP claimed
CN-112062785-A Preparation method of ozapimod and intermediate thereof 广东东阳光药业有限公司 2020-12-11 CN claimed
CN-111971398-A Enantioselective biocatalytic preparation of 4-cyano-substituted 1-aminoindan and azanidod 泽尔制药有限公司 2020-11-20 CN claimed
CN-110997645-A Preparation method of ozanimod 埃吉斯制药公司 2020-04-10 CN claimed
US-20200087269-A1 PROCESS FOR THE PRODUCTION OF OZANIMOD EGIS GYOGYSZERGYAR ZRT. (HU) 2020-03-19 US claimed
WO-2019197571-A1 ENANTIOSELECTIVE BIOCATALYTIC PREPARATION OF 4-CYANO-SUBSTITUTED 1-AMINOINDANE AND OZANIMOD UNIVERSITÄT BIELEFELD (DE) 2019-10-17 WO claimed
EP-3553179-A1 ENANTIOSELECTIVE BIOCATALYTIC PREPARATION OF 4-CYANO-SUBSTITUTED 1-AMINOINDANE AND OZANIMOD Universität Bielefeld (DE) 2019-10-16 EP claimed
CN-117843529-B Resolution method of ozagrel hydrochloride intermediate and preparation method of ozagrel hydrochloride Beijing Sunshine Nuohe Pharmaceutical Research Co.,Ltd. (CN) 2026-05-26 CN disclosed
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
EP-3518922-B1 COMPOUNDS AND METHODS FOR TREATING LUPUS RECEPTOS LLC (US) 2026-02-11 EP disclosed
US-12459907-B2 Process for the production of ozanimod EGIS GYOGYSZERGYAR ZRT. (HU) 2025-11-04 US disclosed
EP-1200409-A2 SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS SMITHKLINE BEECHAM PLC (GB) 2002-05-02 EP disclosed
CN-1324359-A Tricyclic carboxamides SMITHKLINE BEECHAM PLC (GB) 2001-11-28 CN disclosed
EP-1102769-A2 TRICYCLIC CARBOXAMIDES SMITHKLINE BEECHAM PLC (GB) 2001-05-30 EP disclosed
WO-2001002366-A2 SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS INTICONVULSANTS SMITHKLINE BEECHAM P.L.C. (GB) 2001-01-11 WO disclosed
WO-2000008020-A2 TRICYCLIC CARBOXAMIDES SMITHKLINE BEECHAM P.L.C. (GB) 2000-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 XDH 733/4885ALDH1A1 3621/4885HPGD 4573/4885
US-12459907-B2 Process for the production of ozanimod OSGEP, BPGM, OTC XDH 2232/4885ALDH1A1 3022/4885HPGD 2677/4885
US-20200087269-A1 PROCESS FOR THE PRODUCTION OF OZANIMOD OSGEP, BPGM, OTC XDH 2232/4885ALDH1A1 3022/4885HPGD 2677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.