Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 11/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10030788 | 0.89 | TUBB1 (0.64) | TUBB1MMP2MMP9MMP8NFKB1 | |
| SCHEMBL17145738 | 0.89 | MMP2 (0.54) | TUBB1MMP2MMP9MMP8NFKB1 | |
| SCHEMBL786868 | 0.89 | TUBB1 (0.52) | TUBB1MMP2MMP9MMP8NFKB1 | |
| SCHEMBL12774233 | 0.86 | TUBB1 (0.50) | TUBB1MMP2MMP9MMP8NFKB1 | |
| SCHEMBL12774239 | 0.86 | TUBB1 (0.63) | TUBB1MMP2MMP9MMP8NFKB1 | |
| SCHEMBL13079742 | 0.84 | TUBB1 (0.65) | TUBB1MMP2MMP9MMP8NFKB1 | |
| SCHEMBL17145749 | 0.83 | MAPT (0.55) | MMP2MMP9MMP8NFKB1ABCB1 | |
| SCHEMBL17145742 | 0.83 | TUBB1 (0.50) | TUBB1MMP2MMP9MMP8NFKB1 | |
| SCHEMBL10136222 | 0.83 | APP (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17145762 | 0.82 | TUBB1 (0.49) | TUBB1MMP2MMP9MMP8NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025661-B1 | FLUOROALKYLOXY-CONTAINING COMBRETASTATIN DERIVATIVES, PREPARATION AND USE THEREOF | ZHEJIANG DADE PHARMACEUTICAL GROUP CO LTD (CN) | 2011-03-16 | — | — | EP | disclosed |