Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 13/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.44 |
| ▸ | TUBB | P07437 | 4/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12810214 | 0.86 | TUBB1 (0.52) | TUBB1CYP1A1PTGS1PTGS2MMP2 | |
| SCHEMBL10030788 | 0.86 | TUBB1 (0.64) | TUBB1CYP1A1PTGS1PTGS2MMP2 | |
| SCHEMBL12774239 | 0.85 | TUBB1 (0.63) | TUBB1CYP1A1PTGS1PTGS2MMP2 | |
| SCHEMBL12593827 | 0.85 | TUBB1 (0.61) | TUBB1CYP1A1PTGS1PTGS2MMP2 | |
| SCHEMBL10030786 | 0.85 | TUBB1 (0.61) | TUBB1CYP1A1PTGS1PTGS2MMP2 | |
| SCHEMBL17145738 | 0.83 | MMP2 (0.54) | TUBB1CYP1A1PTGS1PTGS2MMP2 | |
| SCHEMBL786868 | 0.83 | TUBB1 (0.52) | TUBB1CYP1A1PTGS1PTGS2MMP2 | |
| SCHEMBL13456507 | 0.83 | APP (0.57) | TUBB1CYP1A1PTGS1PTGS2MMP2 | |
| SCHEMBL17145749 | 0.83 | MAPT (0.55) | CYP1A1PTGS1PTGS2MMP2MMP9 | |
| SCHEMBL10135773 | 0.81 | ABCG2 (0.54) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150065727-A1 | THE NEW DERIVATIVES OF (Z)-1,2-DIPHENYLETHENE | UNIWERSYTET MEDYCZNY IM. KAROLA MARCINKOWSKIEGO (PL) | 2015-03-05 | — | — | US | disclosed |
| US-20110054035-A1 | Combination Comprising Combretastatin and Anticancer Agents | AVENTIS PHARMA S.A. (FR) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054035-A1 | Combination Comprising Combretastatin and Anticancer Agents | TEK, FLT4, FLT1 | TUBB1 47/4885CYP1A1 4777/4885PTGS1 1873/4885 |
| US-20150065727-A1 | THE NEW DERIVATIVES OF (Z)-1,2-DIPHENYLETHENE | TUBB1, TUBA1C, TUBB3 | TUBB1 1/4885CYP1A1 3678/4885PTGS1 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.