Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981467 | 0.90 | RORC (0.43) | RORCACSS2MAPK14 | |
| SCHEMBL7982045 | 0.89 | ALPG (0.39) | — | |
| SCHEMBL7981478 | 0.83 | ACSS2 (0.38) | RORCACSS2MAPK14 | |
| SCHEMBL7988236 | 0.82 | JAK2 (0.39) | JAK2JAK1TYK2JAK3ACSS2 | |
| SCHEMBL7982928 | 0.82 | MAPK14 (0.39) | JAK2JAK1TYK2JAK3ACSS2 | |
| SCHEMBL7985159 | 0.81 | MKNK1 (0.37) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL1417571 | 0.81 | ALPG (0.38) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL7978345 | 0.80 | ACSS2 (0.41) | ACSS2KMT2AMAPK14 | |
| SCHEMBL1417622 | 0.79 | RORC (0.42) | RORCACSS2MAPK14 | |
| SCHEMBL7992166 | 0.78 | HSD11B1 (0.37) | RORCACSS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298747-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-03-23 | — | — | EP | disclosed |