Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310670 | 1.00 | SIGMAR1 (0.41) | SIGMAR1CTSLCYP3A4CHRM2HTR1A | |
| SCHEMBL10069163 | 1.00 | SIGMAR1 (0.41) | SIGMAR1CTSLCYP3A4CHRM2HTR1A | |
| SCHEMBL8419059 | 0.86 | SIGMAR1 (0.42) | SIGMAR1CTSLCYP3A4CHRM2HTR1A | |
| SCHEMBL7900384 | 0.82 | CTSL (0.39) | CTSLCTSSCTSK | |
| SCHEMBL24298107 | 0.79 | SIGMAR1 (0.40) | SIGMAR1CTSLCHRM2HTR1AADRA2A | |
| SCHEMBL26829207 | 0.79 | SIGMAR1 (0.40) | SIGMAR1CTSLCHRM2HTR1AADRA2A | |
| SCHEMBL24298108 | 0.79 | SIGMAR1 (0.40) | SIGMAR1CTSLCHRM2HTR1AADRA2A | |
| SCHEMBL25767154 | 0.79 | SIGMAR1 (0.47) | SIGMAR1CYP3A4CHRM2HTR1AADRA2A | |
| SCHEMBL24298254 | 0.76 | CTSL (0.39) | SIGMAR1CTSLMEN1KMT2ACTSS | |
| SCHEMBL26127160 | 0.76 | CTSL (0.39) | SIGMAR1CTSLMEN1KMT2ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205575-B1 | A NOVEL ALPHA-(N-SULFONAMIDO)ACETAMIDE COMPOUND AS AN INHIBITOR OF BETA AMYLOID PEPTIDE PRODUCTION | BRISTOL MYERS SQUIBB CO (US) | 2011-03-16 | — | — | EP | disclosed |