Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.39 |
| ▸ | CTSC | P53634 | 6/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSF | Q9UBX1 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069163 | 0.82 | SIGMAR1 (0.41) | CTSLCTSSCTSK | |
| SCHEMBL12810249 | 0.82 | SIGMAR1 (0.41) | CTSLCTSSCTSK | |
| SCHEMBL310670 | 0.82 | SIGMAR1 (0.41) | CTSLCTSSCTSK | |
| SCHEMBL1688364 | 0.72 | SIGMAR1 (0.39) | CTSLCTSCTSHR | |
| SCHEMBL375592 | 0.70 | DRD2 (0.42) | CTSLCTSCTSHR | |
| SCHEMBL12574579 | 0.69 | TACR1 (0.47) | — | |
| SCHEMBL12261606 | 0.69 | TACR1 (0.47) | — | |
| SCHEMBL8419059 | 0.68 | SIGMAR1 (0.42) | CTSLCTSSCTSKCTSBCTSF | |
| SCHEMBL16900469 | 0.68 | DPP4 (0.55) | TSHR | |
| Hydrochloric Acid SCHEMBL22229344 | 0.68 | TACR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107997-A1 | THIOPHENYL SULFONAMIDES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-09-23 | — | — | WO | disclosed |