Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13765230 | 0.89 | ELANE (0.46) | ELANEADORA3HPGDNPC1RAB9A | |
| SCHEMBL18567241 | 0.81 | ADORA3 (0.45) | ADORA3HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18476724 | 0.80 | ADORA3 (0.42) | ELANEADORA3HPGDNPC1RAB9A | |
| SCHEMBL14532269 | 0.78 | ELANE (0.54) | ELANEADORA3SMN1; SMN2ALDH1A1PPARA | |
| SCHEMBL14781031 | 0.78 | ESR1 (0.57) | ELANEADORA3NPC1RAB9AKMT2A | |
| SCHEMBL18945321 | 0.78 | SLC6A4 (0.49) | ELANEADORA3HPGDSMN1; SMN2KMT2A | |
| SCHEMBL13764948 | 0.78 | ELANE (0.59) | ELANENPC1RAB9AACACBACACA | |
| SCHEMBL18411203 | 0.77 | ADORA3 (0.48) | ELANEADORA3HPGDNPC1RAB9A | |
| SCHEMBL16284135 | 0.76 | CYP2C9 (0.43) | ELANEADORA3HPGDNPC1RAB9A | |
| SCHEMBL21785623 | 0.75 | ADORA3 (0.54) | ELANEADORA3NPC1RAB9AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1770447-B1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY | MITSUBISHI CHEM CORP (JP) | 2011-03-16 | — | — | EP | disclosed |