Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14108149 | 0.85 | ADORA3 (0.51) | ADORA3ESR1HIF1AKMT2ASMN1; SMN2 | |
| SCHEMBL18567241 | 0.85 | ADORA3 (0.45) | ADORA3ESR1KMT2ASMN1; SMN2PPARA | |
| SCHEMBL13765230 | 0.84 | ELANE (0.46) | ADORA3ESR1KMT2ASMN1; SMN2PPARA | |
| SCHEMBL12134134 | 0.83 | ADORA3 (0.53) | ADORA3ESR1KMT2ASMN1; SMN2PPARA | |
| SCHEMBL18476724 | 0.82 | ADORA3 (0.42) | ADORA3ESR1KMT2ASMN1; SMN2PPARA | |
| SCHEMBL10353823 | 0.82 | ADORA3 (0.48) | ADORA3ESR1KMT2ASMN1; SMN2ELANE | |
| SCHEMBL14280383 | 0.79 | ADORA3 (0.45) | ADORA3ESR1HIF1AKMT2ASMN1; SMN2 | |
| SCHEMBL12810378 | 0.77 | ELANE (0.38) | ADORA3ESR1KMT2ASMN1; SMN2PPARA | |
| SCHEMBL13660290 | 0.77 | ADORA3 (0.50) | ADORA3KMT2ASMN1; SMN2PPARAALDH1A1 | |
| SCHEMBL13979409 | 0.77 | ESR1 (0.63) | ADORA3ESR1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022361-A1 | HIGH HEAT POLYCARBONATE COMPOSITIONS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-01-26 | — | — | US | disclosed |