SCHEMBL18567241

SCHEMBL18567241

CC(=O)Oc1ccc(C2(c3ccc(OC(C)C)cc3)CCCCC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 2/20 0.45
▸ KMT2A Q03164 4/20 0.44
▸ POLB P06746 3/20 0.44
▸ NPC1 O15118 2/20 0.44
▸ RAB9A P51151 2/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ MAPT P10636 3/20 0.43
▸ HPGD P15428 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ ESR1 P03372 3/20 0.42
▸ PGR P06401 1/20 0.42
▸ CHRM2 P08172 1/20 0.42
▸ AR P10275 1/20 0.42
▸ CHRM1 P11229 1/20 0.42
▸ SLC6A2 P23975 1/20 0.42
▸ SLC6A3 Q01959 1/20 0.42
▸ LMNA P02545 2/20 0.41
▸ ESR2 Q92731 2/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13765230 0.90 ELANE (0.46) ADORA3KMT2APOLBNPC1RAB9A
SCHEMBL10907042 0.89 ADORA3 (0.52) ADORA3KMT2APOLBNPC1RAB9A
SCHEMBL18411203 0.85 ADORA3 (0.48) ADORA3KMT2APOLBNPC1RAB9A
SCHEMBL18476724 0.85 ADORA3 (0.42) ADORA3KMT2APOLBNPC1RAB9A
SCHEMBL10353823 0.85 ADORA3 (0.48) ADORA3KMT2ANPC1RAB9AMEN1
SCHEMBL15179068 0.84 MAPT (0.54) ADORA3KMT2APOLBNPC1RAB9A
SCHEMBL13242034 0.84 LMNA (0.62) ADORA3KMT2APOLBNPC1RAB9A
SCHEMBL12521524 0.84 ESR1 (0.62) ADORA3KMT2APOLBNPC1RAB9A
SCHEMBL1256640 0.84 ELANE (0.51) ADORA3KMT2APOLBNPC1RAB9A
SCHEMBL279321 0.84 MAPT (0.54) ADORA3KMT2APOLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032323-B2 Image forming apparatus and process cartridge FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-07-09 — — US disclosed
US-11796928-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-10-24 — — US disclosed
EP-2633369-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KK (JP) 2019-08-14 — — EP disclosed
EP-2646877-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KK (JP) 2017-03-01 — — EP disclosed
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