Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899039 | 0.80 | FFAR1 (0.48) | FFAR1FFAR4 | |
| SCHEMBL503325 | 0.80 | TSHR (0.53) | CXCL8AKR1B1TSHR | |
| SCHEMBL29459931 | 0.80 | TSHR (0.53) | CXCL8AKR1B1TSHR | |
| Bromide SCHEMBL8397120 | 0.78 | TSHR (0.51) | CXCL8TSHR | |
| SCHEMBL1142805 | 0.78 | CAMK2A (0.51) | AKR1B1TSHRCAMK2A | |
| SCHEMBL30523650 | 0.78 | CAMK2A (0.51) | AKR1B1TSHRCAMK2A | |
| SCHEMBL2006540 | 0.77 | AKR1B1 (0.43) | CXCL8AKR1B1TSHRSRCCYP26A1 | |
| SCHEMBL5545008 | 0.77 | SRC (0.59) | SRCFFAR1FFAR4RXRARXRB | |
| SCHEMBL2298577 | 0.77 | AKR1B1 (0.43) | CXCL8AKR1B1TSHRSRCCYP26A1 | |
| SCHEMBL348979 | 0.77 | KEAP1 (0.50) | CXCL8AKR1B1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086643-B1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LTD (GB) | 2011-03-23 | — | — | EP | disclosed |