Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | CASP6 | P55212 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12811684 | 0.83 | CTSB (0.43) | CTSBMAPTCASP6POLBAPEX1 | |
| SCHEMBL14039078 | 0.82 | CTSB (0.42) | CTSBMAPTCASP6POLBAPEX1 | |
| SCHEMBL12811693 | 0.82 | CTSB (0.42) | CTSBMAPTCASP6POLBAPEX1 | |
| SCHEMBL28446443 | 0.72 | KDM4E (0.52) | MAPTPOLBALDH1A1KDM4EHSP90AA1 | |
| SCHEMBL12811429 | 0.72 | CTSB (0.36) | CTSBMAPTCASP6POLBLMNA | |
| SCHEMBL12811624 | 0.72 | CTSB (0.36) | CTSBMAPTCASP6POLBLMNA | |
| SCHEMBL14039053 | 0.72 | MAPT (0.36) | CTSBMAPTCASP6POLBAPEX1 | |
| SCHEMBL16997296 | 0.72 | CTSB (0.40) | CTSBMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL17706814 | 0.72 | ALDH1A1 (0.46) | MAPTCASP6LMNAALDH1A1RAB9A | |
| SCHEMBL12811706 | 0.71 | CTSB (0.30) | CTSBMAPTCASP6POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2301921-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2011-03-30 | — | — | EP | disclosed |