Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | CASP6 | P55212 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12811684 | 0.87 | CTSB (0.43) | CTSBMAPTCASP6POLBAPEX1 | |
| SCHEMBL12811693 | 0.86 | CTSB (0.42) | CTSBMAPTCASP6POLBAPEX1 | |
| SCHEMBL14039053 | 0.85 | MAPT (0.36) | CTSBMAPTCASP6POLBAPEX1 | |
| SCHEMBL12811706 | 0.84 | CTSB (0.30) | CTSBMAPTCASP6POLBAPEX1 | |
| SCHEMBL14039080 | 0.84 | MAPK1 (0.38) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12811346 | 0.82 | CTSB (0.40) | CTSBMAPTCASP6POLBAPEX1 | |
| SCHEMBL14039079 | 0.80 | KDM4E (0.36) | POLBKMT2AHPGDMEN1SMN1; SMN2 | |
| SCHEMBL12811624 | 0.76 | CTSB (0.36) | CTSBMAPTCASP6POLBKMT2A | |
| SCHEMBL12811429 | 0.76 | CTSB (0.36) | CTSBMAPTCASP6POLBKMT2A | |
| SCHEMBL28446443 | 0.74 | KDM4E (0.52) | MAPTPOLBKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130020563-A1 | POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
| US-20130020563-A1 | POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
| US-8318323-B2 | Polycyclic compounds and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-8318323-B2 | Polycyclic compounds and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130020563-A1 | POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | KCNC1, EED, BMI1 | CTSB 2954/4885MAPT 1303/4885CASP6 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.