Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.79 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | KLK7 | P49862 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813753 | 1.00 | MEN1 (0.79) | MEN1KMT2APOLBPSMD14USP2 | |
| SCHEMBL1961879 | 0.90 | MEN1 (0.87) | MEN1KMT2APOLBPSMD14MAPT | |
| SCHEMBL1961880 | 0.90 | MEN1 (0.87) | MEN1KMT2APOLBPSMD14MAPT | |
| SCHEMBL17489620 | 0.81 | MEN1 (0.80) | MEN1KMT2APOLBPSMD14MAPT | |
| SCHEMBL12813614 | 0.80 | MAPT (1.00) | MEN1KMT2APOLBUSP2TLR9 | |
| SCHEMBL12813610 | 0.80 | MAPT (1.00) | MEN1KMT2APOLBUSP2TLR9 | |
| SCHEMBL12316853 | 0.79 | MEN1 (0.90) | MEN1KMT2APOLBPSMD14MAPT | |
| SCHEMBL1961886 | 0.78 | MAPT (0.84) | MEN1KMT2APOLBPSMD14MAPT | |
| SCHEMBL1961884 | 0.78 | MAPT (0.84) | MEN1KMT2APOLBPSMD14MAPT | |
| SCHEMBL1960111 | 0.78 | MEN1 (0.80) | MEN1KMT2APOLBUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10316371-B2 | Screening methods for identifying specific Staphylococcus aureus inhibitors | TRANA DISCOVERY, INC. (US) | 2019-06-11 | — | — | US | claimed |
| US-20140163037-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2014-06-12 | — | — | US | claimed |
| EP-2691542-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | Trana Discovery, Inc. (US) | 2014-02-05 | — | — | EP | claimed |
| WO-2012135416-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2012-10-04 | — | — | WO | claimed |
| US-10316371-B2 | Screening methods for identifying specific Staphylococcus aureus inhibitors | TRANA DISCOVERY, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-10316371-B2 | Screening methods for identifying specific Staphylococcus aureus inhibitors | TRANA DISCOVERY, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-20140163037-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140163037-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140163037-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| EP-2691542-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | Trana Discovery, Inc. (US) | 2014-02-05 | — | — | EP | disclosed |
| WO-2012135416-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012135416-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163037-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | NSUN3, RNGTT, TRMT1 | MEN1 3734/4885KMT2A 1190/4885POLB 401/4885 |
| US-10316371-B2 | Screening methods for identifying specific Staphylococcus aureus inhibitors | NSUN3, RNGTT, TRMT1 | MEN1 3734/4885KMT2A 1190/4885POLB 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.