Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606022 | 0.92 | TDP1 (0.60) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| Amiloxate SCHEMBL128150 | 0.91 | TDP1 (0.59) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL35995 | 0.90 | TDP1 (0.62) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL35994 | 0.90 | TDP1 (0.62) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL14698300 | 0.90 | TDP1 (0.62) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL28036638 | 0.89 | TDP1 (0.61) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL28200368 | 0.88 | TDP1 (0.60) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL28313815 | 0.87 | TDP1 (0.58) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL19717781 | 0.87 | TDP1 (0.58) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| Amiloxate SCHEMBL128152 | 0.86 | LMNA (0.57) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965758-B1 | COMPOSITIONS CONTAINING PROTEINS FOR THE TRANSFER/RECYCLING OF STRUCTURALLY MODIFIED LIPIDS, AND THE APPLICATIONS THEREOF | MERZ PHARMA GMBH & CO KGAA (DE) | 2012-03-07 | — | — | EP | disclosed |