Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amiloxate SCHEMBL128151 | 0.91 | TDP1 (0.71) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| Octinoxate SCHEMBL420736 | 0.87 | TDP1 (0.68) | TDP1LMNAKDM4EALDH1A1HPGD | |
| Amiloxate SCHEMBL19899316 | 0.86 | LMNA (0.71) | TDP1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL7606022 | 0.85 | TDP1 (0.60) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| Octocrylene SCHEMBL5160335 | 0.85 | ALDH1A1 (0.51) | TDP1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL14562456 | 0.84 | NFE2L2 (0.52) | TDP1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL62156 | 0.84 | NFE2L2 (0.52) | TDP1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL31710835 | 0.84 | NFE2L2 (0.52) | TDP1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL14698300 | 0.82 | TDP1 (0.62) | TDP1LMNASMN1; SMN2MAOBTAS1R3 | |
| SCHEMBL35994 | 0.82 | TDP1 (0.62) | TDP1LMNASMN1; SMN2MAOBTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965758-B1 | COMPOSITIONS CONTAINING PROTEINS FOR THE TRANSFER/RECYCLING OF STRUCTURALLY MODIFIED LIPIDS, AND THE APPLICATIONS THEREOF | MERZ PHARMA GMBH & CO KGAA (DE) | 2012-03-07 | — | — | EP | disclosed |