Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amiloxate SCHEMBL128151 | 0.86 | TDP1 (0.71) | LMNATDP1TAS1R3TAS1R1SMN1; SMN2 | |
| Cinnamic Acid SCHEMBL14166230 | 0.83 | EGFR (0.44) | LMNASMN1; SMN2ALDH1A1CASP3SENP7 | |
| Amiloxate SCHEMBL128150 | 0.82 | TDP1 (0.59) | LMNATDP1KMT2AMEN1TAS1R3 | |
| SCHEMBL25221842 | 0.81 | LMNA (0.56) | LMNATDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL14698302 | 0.81 | CTSK (0.44) | LMNATDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL62157 | 0.81 | CTSK (0.44) | LMNATDP1KMT2AMEN1ALDH1A1 | |
| 4-Methoxycinnamic Acid SCHEMBL21195188 | 0.79 | TDP1 (0.55) | LMNATDP1KMT2AMEN1TAS1R3 | |
| SCHEMBL7606022 | 0.78 | TDP1 (0.60) | LMNATDP1TAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL19717782 | 0.78 | CTSK (0.42) | LMNATDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30954277 | 0.77 | TDP1 (0.41) | LMNATDP1TAS1R3TAS1R1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965758-B1 | COMPOSITIONS CONTAINING PROTEINS FOR THE TRANSFER/RECYCLING OF STRUCTURALLY MODIFIED LIPIDS, AND THE APPLICATIONS THEREOF | MERZ PHARMA GMBH & CO KGAA (DE) | 2012-03-07 | — | — | EP | disclosed |